Where do I even begin.
Clear everything off the bed and make it. Change the sheets if you have a spare set.
Gather up the laundry. Start a load if you have access to a washer and dryer, otherwise just get it all into one place: the hamper, laundry baskets, a bag, whatever. Put away/hang up any clean clothes. Take a break.
Gather up anything that’s obviously trash and take it out or recycle it.
Start with your nightstand. Clear off the surface, putting things back or throwing them away/recycling them as you go. Take a break
Next, get to the shelves at the foot of your bed. Organize them, and make space for other things to go. Take a break.
Beginning in front of your nightstand, deal with each pile of stuff or a one foot square of floor at a time. Take a break every 20 minutes. If something doesn’t have a home, find it one before moving on to the next pile.
When you have enough floor exposed, vacuum.
You do not have to do this all in one day. Do what you can, and then come back to it.